Little Zizou is a story of 2 Parsi Families - the Khodaijis and Pressvalas. Cyrus Khodaiji (Sohrab Ardeshir) who claims to be a religious Parsi healer wanting to establish a liberation organization for the Parsis is often troubled by his Parsi counterpart Boman Pressvala (Boman Irani) who owns a Parsi news journal and is against the values and principles of Cyrus Khodaiji and makes sure to print articles against him every time. The youngest little boy of the Khodaiji family is Xerxes or Little Zizou (Jahan Bativala), a football freak who idolizes Zinedine Zidane and hopes to meet the football star if he ever toured Mumbai. His brother Artaxerxes (Imad Shah), a soft spoken artist and who visualizes life through his weird cartoons and dreams to build a Flight Simulator with his two other friends. The young little girl of the Pressvalas is Liana, who is clever and witty. The story revolves around how things get way too complicated when people react to the articles written by Boman Pressvala.